What is Osimertinib used for?
EGFR-mutation-positive non-small-cell lung cancer (first-line and T790M-resistant)
Targeted therapy for certain EGFR-positive non-small-cell lung cancers. Availability is reviewed against the treating clinician’s prescription.
In simple terms
Osimertinib is a third-generation EGFR tyrosine-kinase inhibitor. It selectively blocks mutated EGFR signalling (including the T790M resistance mutation) that drives certain lung cancers, and crosses into the brain to treat CNS spread.
Brand and medicine details
- Active ingredient
- Osimertinib
- Dispensing location
- Confirmed only if an enquiry can proceed.
- Brand references
- Tagrisso
- Strengths shown
- 40 mg, 80 mg
- Dosage form
- Tablet
A catalogue brand reference does not confirm the manufacturer, pack, source or availability for an individual enquiry. Confirm any proposed substitution with the treating oncology team.
How it may be prescribed
Usual dose is 80 mg once daily, with or without food, as directed by the treating oncologist. Taken continuously while it remains effective.
Possible side effects to discuss with the care team
- Diarrhoea
- Rash and dry skin
- Nail changes, mouth sores
- Less commonly, effects on heart rhythm or lungs (needs monitoring)
Specialist oncology supervision is essential. Regular monitoring (heart, lungs, bloods) is required. Supplied only against a valid specialist prescription.
Common questions about Osimertinib
Is Osimertinib here genuine, or a copy?
It is genuine. Osimertinib is referred only as the originator medicine, made by the company that developed it. Medrack refers only licensed medicine from a controlled supply chain. The exact brand, manufacturer and pack are confirmed at the enquiry stage, and any proposed medicine should be reviewed with the treating oncology team.
Do I need a prescription for Osimertinib?
Yes. Osimertinib is a prescription medicine. You can start an enquiry before you have the prescription in hand, but nothing proceeds until a current prescription issued in the patient's name has been received and checked. You upload it privately as part of the enquiry.
What happens after you enquire
Every enquiry is assessed individually. A listing on this page does not confirm availability, a dispensing pharmacy or a delivery.
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You send an enquiry
Add the prescribed medicine and upload the current prescription. This records a request for assessment, not an order.
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We check the prescription
The medicine, prescription, patient details, destination and supporting documentation are reviewed case by case.
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We prepare a referral and written terms
Any proposal identifies the responsible dispensing party, the dispensing country, the total charges and the cancellation terms.
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You confirm and pay
Nothing proceeds until you accept the disclosed terms. Payment is requested only after that written summary has been provided.
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Dispatch and delivery
Dispatch and delivery dates are estimates. Timing can change with availability, documentation, customs or regulatory decisions outside our control.
Full detail is in delivery and fulfilment, order and fulfilment terms and cancellation and refunds.
Before you send an enquiry
These guides explain what to check and what to ask, so the enquiry arrives complete.
- How to read the medicine name on a cancer prescription A practical, non-medical guide for patients and caregivers who need to identify the medicine, strength and information needed for a prescription-led access request.
- What to ask the oncology team about a medicine A patient and caregiver checklist for discussing a prescribed oral cancer medicine with the treating oncology team.
- How to prepare a cancer medicine access request A simple checklist for patients and caregivers preparing a prescription-led medicine information or access request.
